Identification of Key Uric Acid Synthesis Pathway in a Unique Mutant Silkworm Bombyx mori Model of Parkinson’s Disease

Plasma uric acid (UA) levels decrease following clinical progression and stage development of Parkinson’s disease (PD). However, the molecular mechanisms underlying decreases in plasma UA levels remain unclear, and the potential to apply mutagenesis to a PD model has not previously been discovered....

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Main Authors: Tabunoki, Hiroko, Ono, Hiromasa, Ode, Hiroaki, Ishikawa, Kazuhiro, Kawana, Natsuki, Banno, Yutaka, Shimada, Toru, Nakamura, Yuki, Yamamoto, Kimiko, Satoh, Jun-ichi, Bono, Hidemasa
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722175/
https://ncbi.nlm.nih.gov/pubmed/23894418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069130
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