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Mutation Types and Aging Differently Affect Revertant Fiber Expansion in Dystrophic Mdx and Mdx52 Mice

Duchenne muscular dystrophy (DMD), one of the most common and lethal genetic disorders, and the mdx mouse myopathies are caused by a lack of dystrophin protein. These dystrophic muscles contain sporadic clusters of dystrophin-expressing revertant fibers (RFs), as detected by immunohistochemistry. RF...

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Bibliographische Detailangaben
Hauptverfasser: Echigoya, Yusuke, Lee, Joshua, Rodrigues, Merryl, Nagata, Tetsuya, Tanihata, Jun, Nozohourmehrabad, Ashkan, Panesar, Dharminder, Miskew, Bailey, Aoki, Yoshitsugu, Yokota, Toshifumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722172/
https://ncbi.nlm.nih.gov/pubmed/23894429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069194
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