Mutation Types and Aging Differently Affect Revertant Fiber Expansion in Dystrophic Mdx and Mdx52 Mice

Duchenne muscular dystrophy (DMD), one of the most common and lethal genetic disorders, and the mdx mouse myopathies are caused by a lack of dystrophin protein. These dystrophic muscles contain sporadic clusters of dystrophin-expressing revertant fibers (RFs), as detected by immunohistochemistry. RF...

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Detalhes bibliográficos
Main Authors: Echigoya, Yusuke, Lee, Joshua, Rodrigues, Merryl, Nagata, Tetsuya, Tanihata, Jun, Nozohourmehrabad, Ashkan, Panesar, Dharminder, Miskew, Bailey, Aoki, Yoshitsugu, Yokota, Toshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722172/
https://ncbi.nlm.nih.gov/pubmed/23894429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069194
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