Combination Therapy with Local Radiofrequency Ablation and Systemic Vaccine Enhances Antitumor Immunity and Mediates Local and Distal Tumor Regression

PURPOSE: Radiofrequency ablation (RFA) is a minimally invasive energy delivery technique increasingly used for focal therapy to eradicate localized disease. RFA-induced tumor-cell necrosis generates an immunogenic source of tumor antigens known to induce antitumor immune responses. However, RFA-indu...

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Detalhes bibliográficos
Main Authors: Gameiro, Sofia R., Higgins, Jack P., Dreher, Matthew R., Woods, David L., Reddy, Goutham, Wood, Bradford J., Guha, Chandan, Hodge, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722166/
https://ncbi.nlm.nih.gov/pubmed/23894654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070417
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