Active vaccination with vaccinia virus A33 protects mice against lethal vaccinia and ectromelia viruses but not against cowpoxvirus; elucidation of the specific adaptive immune response

Vaccinia virus protein A33 (A33(VACV)) plays an important role in protection against orthopoxviruses, and hence is included in experimental multi-subunit smallpox vaccines. In this study we show that single-dose vaccination with recombinant Sindbis virus expressing A33(VACV), is sufficient to protec...

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Bibliografiske detaljer
Main Authors: Paran, Nir, Lustig, Shlomo, Zvi, Anat, Erez, Noam, Israely, Tomer, Melamed, Sharon, Politi, Boaz, Ben-Nathan, David, Schneider, Paula, Lachmi, Batel, Israeli, Ofir, Stein, Dana, Levin, Reuven, Olshevsky, Udy
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722049/
https://ncbi.nlm.nih.gov/pubmed/23842430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-229
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