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Modulation of host natural killer cell functions in breast cancer via prostaglandin E(2) receptors EP2 and EP4

Breast malignancies often have high levels of COX-2. The COX-2 product prostaglandin E(2) (PGE(2)) contributes to the high metastatic capacity of breast tumors. Our published data indicates that inhibiting either PGE(2) production or PGE(2)-mediated signaling through the PGE(2) receptor EP4 (one of...

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Hlavní autoři: Holt, Dawn, Ma, Xinrong, Kundu, Namita, Collin, Peter D, Fulton, Amy M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721982/
https://ncbi.nlm.nih.gov/pubmed/22306906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e318247a5e9
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