Genetic Heterogeneity in Colorectal Cancer Associations in Americans of African vs. European Descent

BACKGROUND & AIMS: Genome-wide association studies of colorectal cancer (CRC) have identified risk variants in 10 genomic regions. None of these studies included African Americans, who have the highest incidence and mortality from CRC in the US. For the 10 genomic regions, we performed an associ...

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Bibliografiske detaljer
Main Authors: Kupfer, Sonia S., Anderson, Jeffrey R., Hooker, Stanley, Skol, Andrew, Kittles, Rick A., Keku, Temitope O., Sandler, Robert S., Ellis, Nathan A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721963/
https://ncbi.nlm.nih.gov/pubmed/20659471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.07.038
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