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Detection of Intergenerational Genetic Effects with Application to HLA-B Matching as a Risk Factor for Schizophrenia

BACKGROUND AND METHODS: Association studies using unrelated individuals cannot detect intergenerational genetic effects contributing to disease. To detect these effects, we improve the extended maternal-fetal genotype (EMFG) incompatibility test to estimate any combination of maternal effects, offsp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Childs, Erica J., Sobel, Eric M., Palmer, Christina G.S., Sinsheimer, Janet S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721948/
https://ncbi.nlm.nih.gov/pubmed/22004985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000332051
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