d-Serine in Glia and Neurons Derives from 3-Phosphoglycerate Dehydrogenase

d-Serine is an endogenous ligand for NMDARs generated from l-serine by the enzyme serine racemase (Srr). Both neuronal and glial localizations have been reported for d-serine and Srr. 3-Phosphoglycerate dehydrogenase is an exclusively astrocytic enzyme that catalyzes the first committed step of l-se...

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Autores principales: Ehmsen, Jeffrey T., Ma, Ting Martin, Sason, Hagit, Rosenberg, Dina, Ogo, Tadashi, Furuya, Shigeki, Snyder, Solomon H., Wolosker, Herman
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2013
Materias:
Brief Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721849/
https://ncbi.nlm.nih.gov/pubmed/23884950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4914-12.2013
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