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The Membrane-Active Tri-Block Copolymer Pluronic F-68 Profoundly Rescues Rat Hippocampal Neurons from Oxygen–Glucose Deprivation-Induced Death through Early Inhibition of Apoptosis

Pluronic F-68, an 80% hydrophilic member of the Pluronic family of polyethylene-polypropylene-polyethylene tri-block copolymers, protects non-neuronal cells from traumatic injuries and rescues hippocampal neurons from excitotoxic and oxidative insults. F-68 interacts directly with lipid membranes an...

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Detalhes bibliográficos
Main Authors: Shelat, Phullara B., Plant, Leigh D., Wang, Janice C., Lee, Elizabeth, Marks, Jeremy D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721839/
https://ncbi.nlm.nih.gov/pubmed/23884935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5731-12.2013
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