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Mechanism of synergistic cell killing when methotrexate precedes cytosine arabinoside: study of L1210 and human leukemic cells.

Synergistic killing of L1210 cells occurs when methotrexate (MTX) is administered just before 1-beta-D-arabinofuranosylcytosine (Ara-C). This pehnomenon is dependent upon both the dose and time of exposure to MTX. Such increased killing of cells can be explained by the enhanced intracellular accumul...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cadman, E, Eiferman, F
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1979
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC372183/
https://ncbi.nlm.nih.gov/pubmed/288743
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