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Pharmacology of Rasagiline, a New MAO-B Inhibitor Drug for the Treatment of Parkinson’s Disease with Neuroprotective Potential

Rasagiline (Azilect) is a highly selective and potent propargylamine inhibitor of monoamine oxidase (MAO) type B. Like other similar propargylamine inhibitors, rasagiline binds covalently to the N5 nitrogen of the flavin residue of MAO, resulting in irreversible inactivation of the enzyme. Therapeut...

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Dettagli Bibliografici
Autore principale: Finberg, John P.M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rambam Health Care Campus 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721659/
https://ncbi.nlm.nih.gov/pubmed/23908775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5041/RMMJ.10003
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