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Pharmacology of Rasagiline, a New MAO-B Inhibitor Drug for the Treatment of Parkinson’s Disease with Neuroprotective Potential
Rasagiline (Azilect) is a highly selective and potent propargylamine inhibitor of monoamine oxidase (MAO) type B. Like other similar propargylamine inhibitors, rasagiline binds covalently to the N5 nitrogen of the flavin residue of MAO, resulting in irreversible inactivation of the enzyme. Therapeut...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Rambam Health Care Campus
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3721659/ https://ncbi.nlm.nih.gov/pubmed/23908775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5041/RMMJ.10003 |
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