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Nkx2-1 Represses a Latent Gastric Differentiation Program in Lung Adenocarcinoma
Tissue-specific differentiation programs become dysregulated during cancer evolution. The transcription factor Nkx2-1 is a master regulator of pulmonary differentiation that is downregulated in poorly differentiated lung adenocarcinoma. Here we use conditional murine genetics to determine how the id...
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主要な著者: | , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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2013
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3721642/ https://ncbi.nlm.nih.gov/pubmed/23523371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.02.018 |
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