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Role of Cytochrome P-450 in Alveolar Hypoxic Pulmonary Vasoconstriction in Dogs

Alveolar hypoxia induces pulmonary vasoconstriction by an unknown mechanism. Cytochrome P-450 (C-P450) is found in the lung and may modify pulmonary vascular tone via its sensitivity to changes in oxygen tension or by affecting metabolism of a chemical mediator. Metyrapone and carbon monoxide are bo...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Miller, Matthew A., Hales, Charles A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1979
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372164/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/457876/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109507
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