Usp18 deficient mammary epithelial cells create an antitumour environment driven by hypersensitivity to IFN-λ and elevated secretion of Cxcl10

The theory of cancer immunoediting refers to mechanisms by which the immune system can suppress or promote tumour progression. A major challenge for the development of novel cancer immunotherapies is to find ways to exploit the immune system's antitumour activity while concomitantly reducing it...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Burkart, Christoph, Arimoto, Kei-ichiro, Tang, Tingdong, Cong, Xiuli, Xiao, Nengming, Liu, Yun-Cai, Kotenko, Sergei V, Ellies, Lesley G, Zhang, Dong-Er
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2013
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721472/
https://ncbi.nlm.nih.gov/pubmed/23681607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201864
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