IL-20 receptor signaling inhibits cutaneous IL-1β and IL-17A production to promote methicillin-resistant Staphylococcus aureus infection

Staphylococcus aureus causes the majority of human skin and soft tissue infections, and is a major infectious cause of mortality. Host defense mechanisms against S. aureus are incompletely understood. Interleukin (IL)-19, -20 and -24 signal through type I and type II IL-20 receptors and are associat...

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Main Authors: Myles, Ian A., Fontecilla, Natalia M., Valdez, Patricia A., Vithayathil, Paul J., Naik, Shruti, Belkaid, Yasmine, Ouyang, Wenjun, Datta, Sandip K.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721434/
https://ncbi.nlm.nih.gov/pubmed/23793061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2637
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