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Position-Effect Variegation, Heterochromatin Formation, and Gene Silencing in Drosophila
Position-effect variegation (PEV) results when a gene normally in euchromatin is juxtaposed with heterochromatin by rearrangement or transposition. When heterochromatin packaging spreads across the heterochromatin/euchromatin border, it causes transcriptional silencing in a stochastic pattern. PEV i...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3721279/ https://ncbi.nlm.nih.gov/pubmed/23906716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a017780 |
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