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An integrated approach to identify causal network modules of complex diseases with application to colorectal cancer

BACKGROUND: Many methods have been developed to identify disease genes and further module biomarkers of complex diseases based on gene expression data. It is generally difficult to distinguish whether the variations in gene expression are causative or merely the effect of a disease. The limitation o...

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Autores principales: Wen, Zhenshu, Liu, Zhi-Ping, Liu, Zhengrong, Zhang, Yan, Chen, Luonan
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Group 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721155/
https://ncbi.nlm.nih.gov/pubmed/22967703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/amiajnl-2012-001168
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