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Calpains mediate axonal cytoskeleton disintegration during Wallerian degeneration

In both the central nervous system (CNS) and peripheral nervous system (PNS), transected axons undergo Wallerian degeneration. Even though Augustus Waller first described this process after transection of axons in 1850, the molecular mechanisms may be shared, at least in part, by many human diseases...

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Detalhes bibliográficos
Main Authors: Ma, Marek, Ferguson, Toby A., Schoch, Kathleen M., Li, Jian, Qian, Yaping, Shofer, Frances S., Saatman, Kathryn E., Neumar, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721029/
https://ncbi.nlm.nih.gov/pubmed/23542511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.03.009
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