Calpains mediate axonal cytoskeleton disintegration during Wallerian degeneration

In both the central nervous system (CNS) and peripheral nervous system (PNS), transected axons undergo Wallerian degeneration. Even though Augustus Waller first described this process after transection of axons in 1850, the molecular mechanisms may be shared, at least in part, by many human diseases...

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Bibliografiske detaljer
Main Authors: Ma, Marek, Ferguson, Toby A., Schoch, Kathleen M., Li, Jian, Qian, Yaping, Shofer, Frances S., Saatman, Kathryn E., Neumar, Robert W.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721029/
https://ncbi.nlm.nih.gov/pubmed/23542511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.03.009
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