Associations between a Polymorphism in the Pleiotropic GCKR and Age-Related Phenotypes: The HALCyon Programme

BACKGROUND: The glucokinase regulatory protein encoded by GCKR plays an important role in glucose metabolism and a single nucleotide polymorphism (SNP) rs1260326 (P446L) in the gene has been associated with several age-related biomarkers, including triglycerides, glucose, insulin and apolipoproteins...

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Bibliographic Details
Main Authors: Alfred, Tamuno, Ben-Shlomo, Yoav, Cooper, Rachel, Hardy, Rebecca, Deary, Ian J., Elliott, Jane, Harris, Sarah E., Kivimaki, Mika, Kumari, Meena, Power, Chris, Starr, John M., Kuh, Diana, Day, Ian N. M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720952/
https://ncbi.nlm.nih.gov/pubmed/23894584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070045
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