Unique Gene Expression and MR T(2) Relaxometry Patterns Define Chronic Murine Dextran Sodium Sulphate Colitis as a Model for Connective Tissue Changes in Human Crohn’s Disease

INTRODUCTION: Chronically relapsing inflammation, tissue remodeling and fibrosis are hallmarks of inflammatory bowel diseases. The aim of this study was to investigate changes in connective tissue in a chronic murine model resulting from repeated cycles of dextran sodium sulphate (DSS) ingestion, to...

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Main Authors: Breynaert, Christine, Dresselaers, Tom, Perrier, Clémentine, Arijs, Ingrid, Cremer, Jonathan, Van Lommel, Leentje, Van Steen, Kristel, Ferrante, Marc, Schuit, Frans, Vermeire, Séverine, Rutgeerts, Paul, Himmelreich, Uwe, Ceuppens, Jan L., Geboes, Karel, Van Assche, Gert
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720888/
https://ncbi.nlm.nih.gov/pubmed/23894361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068876
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