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Standard Pentostatin Dose Reductions in Renal Insufficiency are not Adequate: Selected Patients with Steroid-Refractory Acute Graft-versus-Host Disease
BACKGROUND AND OBJECTIVE: Pentostatin is an irreversible inhibitor of adenosine deaminase and has been used to prevent graft-versus-host disease (GVHD) and to treat both acute and chronic GVHD. Dose reduction equations for patients with renal insufficiency are based on few patients with limited phar...
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Glavni autori: | , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2013
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3720841/ https://ncbi.nlm.nih.gov/pubmed/23588536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-013-0064-7 |
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