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Cardiotrophin-1 Induces Matrix Metalloproteinase-1 in Human Aortic Endothelial Cells

Rupture of an atherosclerotic plaque is a key event in the development of cardiovascular disorders, in which matrix metalloproteinase-1 (MMP-1) plays a crucial role by degradation of extracellular matrix resulting in plaque instability. Cardiotrophin-1 (CT-1), a member of interleukin-6-type proinfla...

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Hlavní autoři: Tokito, Akinori, Jougasaki, Michihisa, Ichiki, Tomoko, Hamasaki, Shuichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720803/
https://ncbi.nlm.nih.gov/pubmed/23935888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068801
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