Effect of ginger root on cyclooxygenase-1 and 15-hydroxyprostaglandin dehydrogenase expression in colonic mucosa of humans at normal and increased risk of colorectal cancer

OBJECTIVES: Elevated tissue levels of prostaglandin E(2) (PGE(2)), produced by cyclooxygenase (COX) are an early event in colorectal cancer (CRC). Data suggest the efficacy of non-steroidal anti-inflammatory (NSAIDs) drugs, which inhibit COX activity, as cancer preventives; however, side effects of...

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Huvudupphovsmän: Jiang, Yan, Turgeon, D. Kim, Wright, Benjamin D., Sidahmed, Elkhansa, Ruffin, Mack T., Brenner, Dean E., Sen, Ananda, Zick, Suzanna M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720765/
https://ncbi.nlm.nih.gov/pubmed/23222413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CEJ.0b013e32835c829b
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