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Relationship of receptor affinity to the modulation of thyroid hormone nuclear receptor levels and growth hormone synthesis by L-triiodothyronine and iodothyronine analogues in cultured GH1 cells.

We have previously demonstrated that L-triiodothyronine (L-T3) induces an increase in growth hormone synthesis and messenger RNA in cultured GH1 cells, a rat pituitary cell line. In addition to regulating the growth hormone response, L-T3 elicits a time- and dose-dependent reduction in the level of...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Samuels, H H, Stanley, F, Casanova, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1979
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372072/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/221536/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109418
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