Selective accumulation of aluminum in cerebral arteries in Alzheimer’s disease (AD)

Once biologically available aluminum bypasses gastrointestinal and blood-brain barriers, this environmentally-abundant neurotoxin has an exceedingly high affinity for the large pyramidal neurons of the human brain hippocampus. This same anatomical region of the brain is also targeted by the earliest...

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Main Authors: Bhattacharjee, S., Zhao, Yuhai, Hill, James M., Culicchia, Frank, Kruck, Theodore P. A., Percy, Maire E., Pogue, Aileen I., Walton, J.R., Lukiw, Walter J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720708/
https://ncbi.nlm.nih.gov/pubmed/23764827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2013.05.007
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