Functional Characterization of Stromal Osteopontin in Melanoma Progression and Metastasis

BACKGROUND: Recent studies demonstrated that not only tumor derived- but stroma derived factors play crucial role in cancer development. Osteopontin (OPN) is a secreted non-collagenous, sialic acid rich, chemokine-like phosphoglycoprotein that facilitates cell-matrix interactions and promotes tumor...

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Bibliographic Details
Main Authors: Kumar, Santosh, Sharma, Priyanka, Kumar, Dhiraj, Chakraborty, Goutam, Gorain, Mahadeo, Kundu, Gopal C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720680/
https://ncbi.nlm.nih.gov/pubmed/23935934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069116
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