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Specific Inhibition of the Polymorphonuclear Leukocyte Chemotactic Response to Hydroxy-Fatty Acid Metabolites of Arachidonic Acid by Methyl Ester Derivatives

The human polymorphonuclear (PMN) leukocyte chemotactic activity of the hydroxy-fatty acid metabolites of arachidonic acid, 12-l-hydroxy-5,8,10-heptadecatrienoic acid (HHT) and 12-l-hydroxy-5,8,10,14-eicosatetraenoic acid (HETE), is eliminated by methylation. Both methyl esters are specific competit...

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Detalhes bibliográficos
Main Authors: Goetzl, Edward J., Valone, Frank H., Reinhold, Vernon N., Gorman, Robert R.
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC372066/
https://ncbi.nlm.nih.gov/pubmed/447841
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