Selection of pfdhfr/pfdhps alleles and declining artesunate/sulphadoxine-pyrimethamine efficacy against Plasmodium falciparum eight years after deployment in eastern Sudan

BACKGROUND: Artesunate/sulphadoxine-pyrimethamine (AS/SP) has been the first-line treatment for falciparum malaria in Sudan since 2004. The impact of this combination on anti-malarial resistance-associated molecular markers has not been investigated. In this study, an evaluation of the efficacy and...

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Detalhes bibliográficos
Main Authors: Gadalla, Nahla B, Abdallah, Tajeldin M, Atwal, Sharanjeet, Sutherland, Colin J, Adam, Ishag
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720549/
https://ncbi.nlm.nih.gov/pubmed/23870667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-255
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