Population pharmacokinetics of mefloquine, piperaquine and artemether-lumefantrine in Cambodian and Tanzanian malaria patients

BACKGROUND: Inter-individual variability in plasma concentration-time profiles might contribute to differences in anti-malarial treatment response. This study investigated the pharmacokinetics of three different forms of artemisinin combination therapy (ACT) in Tanzania and Cambodia to quantify and...

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Main Authors: Staehli Hodel, Eva Maria, Guidi, Monia, Zanolari, Boris, Mercier, Thomas, Duong, Socheat, Kabanywanyi, Abdunoor M, Ariey, Frédéric, Buclin, Thierry, Beck, Hans-Peter, Decosterd, Laurent A, Olliaro, Piero, Genton, Blaise, Csajka, Chantal
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720542/
https://ncbi.nlm.nih.gov/pubmed/23841950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-235
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