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Delayed androgen treatment prolongs survival in murine lupus.

Female NZB/NZW F1 mice were treated as adults with 5-alpha-dihydrotestosterone powder packed into subcutaneous implants. Two treatment protocols were followed: (a) 3-mo-old mice received 6 mg of androgen, and (b) 6-mo-old mice were castrated and given 12 mg of androgen. Sham females received empty i...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Roubinian, J R, Talal, N, Greenspan, J S, Goodman, J R, Siiteri, P K
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372031/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/447833/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109390
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