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A Comparison of Aggregatibacter actinomycetemcomitans (Aa) Virulence Traits in a Rat Model for Periodontal Disease

Our aim was to explore the effects of Cytolethal Distending toxin (Cdt) in a well established rat model of periodontal disease where leukotoxin (LtxA) was thought to have no known effect. In vitro studies, were used to assess CdtB activity using Aa Leukotoxin as a negative control. These studies sho...

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Main Authors: Schreiner, Helen, Li, Yu, Cline, Joshua, Tsiagbe, Vincent K., Fine, Daniel H.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720274/
https://ncbi.nlm.nih.gov/pubmed/23936002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069382
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