Mitofusion-2-mediated alleviation of insulin resistance in rats through reduction in lipid intermediate accumulation in skeletal muscle

BACKGROUND: Increased lipid accumulation and mitochondrial dysfunction within skeletal muscle have been shown to be strongly associated with insulin resistance. However, the role of mitofusion-2 (MFN2), a key factor in mitochondrial function and energy metabolism, in skeletal muscle lipid intermedia...

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Main Authors: Zhang, Xuemei, Wang, Chao, Song, Guangyao, Gan, Kexin, Kong, Dexian, Nie, Qian, Ren, Luping
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720227/
https://ncbi.nlm.nih.gov/pubmed/23815800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-20-45
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