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The role of BRCA1 and BRCA2 in prostate cancer

One of the strongest risk factors for prostate cancer is a family history of the disease. Germline mutations in the breast cancer predisposition gene 2 (BRCA2) are the genetic events known to date that confer the highest risk of prostate cancer (8.6-fold in men ≤65 years). Although the role of BRCA2...

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Detalhes bibliográficos
Main Authors: Castro, Elena, Eeles, Rosalind
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720154/
https://ncbi.nlm.nih.gov/pubmed/22522501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2011.150
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