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Downregulation of cold-inducible RNA-binding protein activates mitogen-activated protein kinases and impairs spermatogenic function in mouse testes

Cold-inducible RNA-binding protein (CIRP) is an RNA-binding protein that is expressed in normal testes and downregulated after heat stress caused by cryptorchidism, varicocele or environmental temperatures. The purpose of this study was to investigate the functions of CIRP in the testes. We employed...

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Detalhes bibliográficos
Main Authors: Xia, Zhi-Ping, Zheng, Xin-Min, Zheng, Hang, Liu, Xiao-Jun, Liu, Gui-Yong, Wang, Xing-Huan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720101/
https://ncbi.nlm.nih.gov/pubmed/23001445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2012.71
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