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Alloreactive CD8 T cells rescued from apoptosis during co-stimulation blockade by Toll-like receptor stimulation remain susceptible to Fas-induced cell death

Blockade of co-stimulatory signals to T cells is extremely effective for the induction of transplantation tolerance in immunologically naive rodents. However, infections and inflammation compromise the efficacy of co-stimulation blockade regimens for the induction of tolerance, thereby stimulating t...

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Detalhes bibliográficos
Main Authors: Priyadharshini, Bhavana, Thornley, Thomas B, Daniels, Keith A, Cuthbert, Amy, Welsh, Raymond M, Greiner, Dale L, Brehm, Michael A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719943/
https://ncbi.nlm.nih.gov/pubmed/23190301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12044
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