Excretion-Reuptake Route of β-Hexosaminidase in Normal and I-Cell Disease Cultured Fibroblasts

It has been proposed that in cultured fibroblasts the final packaging of enzymes in lysosomes requires excretion followed by pinocytosis by neighboring cells via a carbohydrate-specific receptor mechanism. It has also been proposed that the abnormally high activity of lysosomal enzymes in the medium...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Autores principales:	Vladutiu, Georgirene D., Rattazzi, Mario C.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 1979
Materias:	Articles
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371993/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/438323/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109341
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