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Induced fit docking, and the use of QM/MM methods in docking

Docking methods are popular computational techniques in drug discovery to identify new active molecules that bind to a given biological target. Although widely used, the predictive reliability of docking methods is often limited by the inability to accurately and efficiently model protein flexibilit...

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Hlavní autoři: Xu, Mengang, Lill, Markus A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719877/
https://ncbi.nlm.nih.gov/pubmed/24050138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddtec.2013.02.003
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