Adenovirus E1A Oncogene Induces Rereplication of Cellular DNA and Alters DNA Replication Dynamics

The oncogenic property of the adenovirus (Ad) transforming E1A protein is linked to its capacity to induce cellular DNA synthesis which occurs as a result of its interaction with several host proteins, including pRb and p300/CBP. While the proteins that contribute to the forced induction of cellular...

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Hlavní autoři: Singhal, Ghata, Leo, Elisabetta, Setty, Saayi Krushna Gadham, Pommier, Yves, Thimmapaya, Bayar
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719816/
https://ncbi.nlm.nih.gov/pubmed/23740993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00879-13
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