MicroRNA 181 Suppresses Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Infection by Targeting PRRSV Receptor CD163

We previously showed that microRNA 181 (miR-181) can inhibit PRRSV replication by directly targeting its genomic RNA. Here, we report that miR-181 can downregulate the PRRSV receptor CD163 in blood monocytes and porcine alveolar macrophages (PAMs) through targeting the 3′ untranslated region (UTR) o...

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Bibliografiska uppgifter
Huvudupphovsmän: Gao, Li, Guo, Xue-kun, Wang, Lianghai, Zhang, Qiong, Li, Ning, Chen, Xin-xin, Wang, Yongqiang, Feng, Wen-hai
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719804/
https://ncbi.nlm.nih.gov/pubmed/23740977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00718-13
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