Treatment of High-Level Gentamicin-Resistant Enterococcus faecalis Endocarditis with Daptomycin plus Ceftaroline

A recurrent case of left-sided endocarditis caused by high-level aminoglycoside-resistant Enterococcus faecalis was successfully treated with ceftaroline and daptomycin. This combination demonstrated excellent synergy in vitro. Mechanistically, ceftaroline enhanced binding of daptomycin to the cell...

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Библиографические подробности
Главные авторы: Sakoulas, George, Nonejuie, Poochit, Nizet, Victor, Pogliano, Joseph, Crum-Cianflone, Nancy, Haddad, Fadi
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
Предметы:
Clinical Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719745/
https://ncbi.nlm.nih.gov/pubmed/23689728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02481-12
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