The Bordetella pertussis Type III Secretion System Tip Complex Protein Bsp22 Is Not a Protective Antigen and Fails To Elicit Serum Antibody Responses during Infection of Humans and Mice

The type III secretion system (T3SS) of pathogenic bordetellae employs a self-associating tip complex protein Bsp22. This protein is immunogenic during infections by Bordetella bronchiseptica and could be used as a protective antigen to immunize mice against B. bronchiseptica challenge. Since low-pa...

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Detalhes bibliográficos
Main Authors: Villarino Romero, Rodrigo, Bibova, Ilona, Cerny, Ondrej, Vecerek, Branislav, Wald, Tomas, Benada, Oldrich, Zavadilova, Jana, Osicka, Radim, Sebo, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719584/
https://ncbi.nlm.nih.gov/pubmed/23690400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00353-13
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