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Haemophilus ducreyi Infection Induces Activation of the NLRP3 Inflammasome in Nonpolarized but Not in Polarized Human Macrophages

Recognition of microbial infection by certain intracellular pattern recognition receptors leads to the formation of a multiprotein complex termed the inflammasome. Inflammasome assembly activates caspase-1 and leads to cleavage and secretion of the proinflammatory cytokines interleukin-1 beta (IL-1β...

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Detalhes bibliográficos
Main Authors: Li, Wei, Katz, Barry P., Bauer, Margaret E., Spinola, Stanley M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719567/
https://ncbi.nlm.nih.gov/pubmed/23753629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00354-13
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