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Escherichia coli Heat-Stable Toxin b Impairs Intestinal Epithelial Barrier Function by Altering Tight Junction Proteins

Escherichia coli heat-stable toxin b (STb) causes diarrhea in animals. STb binds to sulfatide, its receptor, and is then internalized. In the cytoplasm, through a cascade of events, STb triggers the opening of ion channels, allowing ion secretion and water loss and leading to diarrhea. Tight junctio...

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Библиографические подробности
Главные авторы: Ngendahayo Mukiza, Clément, Dubreuil, J. Daniel
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719558/
https://ncbi.nlm.nih.gov/pubmed/23716609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00455-13
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