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Brucella BioR Regulator Defines a Complex Regulatory Mechanism for Bacterial Biotin Metabolism

The enzyme cofactor biotin (vitamin H or B7) is an energetically expensive molecule whose de novo biosynthesis requires 20 ATP equivalents. It seems quite likely that diverse mechanisms have evolved to tightly regulate its biosynthesis. Unlike the model regulator BirA, a bifunctional biotin protein...

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Detalles Bibliográficos
Autores principales: Feng, Youjun, Xu, Jie, Zhang, Huimin, Chen, Zeliang, Srinivas, Swaminath
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719536/
https://ncbi.nlm.nih.gov/pubmed/23729648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00378-13
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