Interleukin-8 Mediates Resistance to Antiangiogenic Agent Sunitinib in Renal Cell Carcinoma

The broad spectrum kinase inhibitor sunitinib is a first-line therapy for advanced clear cell renal cell carcinoma (ccRCC), a deadly form of kidney cancer. Unfortunately, most patients develop sunitinib resistance and progressive disease after about 1 year of treatment. In this study, we evaluated t...

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Autori principali: Huang, Dan, Ding, Yan, Zhou, Ming, Rini, Brian I., Petillo, David, Qian, Chao-Nan, Kahnoski, Richard, Futreal, P. Andrew, Furge, Kyle A., Teh, Bin Tean
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719378/
https://ncbi.nlm.nih.gov/pubmed/20103651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3965
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