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Role of Microtubules in Low Density Lipoprotein Processing by Cultured Cells

The effect of the microtubule inhibitor colchicine on the metabolism of (125)I-low density lipoprotein (LDL) by cultured human skin fibroblasts and aortic medial cells was studied in vitro. Colchicine did not alter the binding of LDL to cell surface receptors. However, the rate of LDL endocytosis wa...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Ostlund, Richard E., Pfleger, Barbara, Schonfeld, Gustav
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1979
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371920/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/216709/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109281
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