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Kinesin-5/Eg5 is important for transport of CARTS from the trans-Golgi network to the cell surface

Here we report that the kinesin-5 motor Klp61F, which is known for its role in bipolar spindle formation in mitosis, is required for protein transport from the Golgi complex to the cell surface in Drosophila S2 cells. Disrupting the function of its mammalian orthologue, Eg5, in HeLa cells inhibited...

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Bibliografski detalji
Glavni autori: Wakana, Yuichi, Villeneuve, Julien, van Galen, Josse, Cruz-Garcia, David, Tagaya, Mitsuo, Malhotra, Vivek
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718972/
https://ncbi.nlm.nih.gov/pubmed/23857769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201303163
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