Kinesin-5/Eg5 is important for transport of CARTS from the trans-Golgi network to the cell surface

Here we report that the kinesin-5 motor Klp61F, which is known for its role in bipolar spindle formation in mitosis, is required for protein transport from the Golgi complex to the cell surface in Drosophila S2 cells. Disrupting the function of its mammalian orthologue, Eg5, in HeLa cells inhibited...

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Bibliografiska uppgifter
Huvudupphovsmän: Wakana, Yuichi, Villeneuve, Julien, van Galen, Josse, Cruz-Garcia, David, Tagaya, Mitsuo, Malhotra, Vivek
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2013
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718972/
https://ncbi.nlm.nih.gov/pubmed/23857769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201303163
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