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Kinesin-5/Eg5 is important for transport of CARTS from the trans-Golgi network to the cell surface

Here we report that the kinesin-5 motor Klp61F, which is known for its role in bipolar spindle formation in mitosis, is required for protein transport from the Golgi complex to the cell surface in Drosophila S2 cells. Disrupting the function of its mammalian orthologue, Eg5, in HeLa cells inhibited...

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Dettagli Bibliografici
Autori principali: Wakana, Yuichi, Villeneuve, Julien, van Galen, Josse, Cruz-Garcia, David, Tagaya, Mitsuo, Malhotra, Vivek
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718972/
https://ncbi.nlm.nih.gov/pubmed/23857769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201303163
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