Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation

The membrane remodeling events required for autophagosome biogenesis are still poorly understood. Because PX domain proteins mediate membrane remodeling and trafficking, we conducted an imaging-based siRNA screen for autophagosome formation targeting human PX proteins. The PX-BAR protein SNX18 was i...

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Bibliografiska uppgifter
Huvudupphovsmän: Knævelsrud, Helene, Søreng, Kristiane, Raiborg, Camilla, Håberg, Karin, Rasmuson, Fredrik, Brech, Andreas, Liestøl, Knut, Rusten, Tor Erik, Stenmark, Harald, Neufeld, Thomas P., Carlsson, Sven R., Simonsen, Anne
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2013
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718966/
https://ncbi.nlm.nih.gov/pubmed/23878278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201205129
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