Underexpression of LATS1 TSG in colorectal cancer is associated with promoter hypermethylation

AIM: To investigate large tumor suppressor 1 (LATS1) expression, promoter hypermethylation, and microsatellite instability in colorectal cancer (CRC). METHODS: RNA was isolated from tumor tissue of 142 CRC patients and 40 colon mucosal biopsies of healthy controls. After reverse transcription, quant...

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Detalhes bibliográficos
Main Authors: Wierzbicki, Piotr M, Adrych, Krystian, Kartanowicz, Dorota, Stanislawowski, Marcin, Kowalczyk, Anna, Godlewski, Janusz, Skwierz-Bogdanska, Iwona, Celinski, Krzysztof, Gach, Tomasz, Kulig, Jan, Korybalski, Bartlomiej, Kmiec, Zbigniew
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2013
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Brief Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718905/
https://ncbi.nlm.nih.gov/pubmed/23885148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v19.i27.4363
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