Increased CD4(+) T Cell Co-Inhibitory Immune Receptor CEACAM1 in Neonatal Sepsis and Soluble-CEACAM1 in Meningococcal Sepsis: A Role in Sepsis-Associated Immune Suppression?

The co-inhibitory immune receptor carcinoembryonic antigen-related cell-adhesion molecule 1 (CEACAM1) and its self-ligand CEACAM1 can suppress T cell function. Suppression of T cell function in sepsis is well documented. Late-onset neonatal sepsis in VLBW-infants was associated with an increased per...

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Main Authors: van der Flier, Michiel, Sharma, Dyana B., Estevão, Silvia, Emonts, Marieke, Rook, Denise, Hazelzet, Jan A., van Goudoever, Johannes B., Hartwig, Nico G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718779/
https://ncbi.nlm.nih.gov/pubmed/23894299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068294
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